Polymer Effect on Antimicrobial Agents Used inDentifrices
유수민, 황경숙, 안금선,
소속 상세정보
유수민 ( Yoo Su-Min ) - Kyungdong University Department of Dental Hygiene
황경숙 ( Hwang Kyung-Sook ) - Shinhan University Department of Dental Technology
안금선 ( Ahn Geum-Sun ) - Kyungbok University Department of Dental Hygiene
KMID : 1157520140100020109
Abstract
Objective: In this study, the anti-microbial effects of cetylpyridinium chloride (CPC), chlorhexidine, and polymer-combined CPC were compared as a bioactive component of dentifrices.
Methods: Hydroxyapatite disks were coated with 1% mucin for 30 minutes and then OD (optical density) values were meas-ured in order to compare the antimicrobial effects of CPC, chlorhexidine and polymer-combined CPC.
Results: The OD values of chlorhexidine and polymer-combined CPC treated sample showed statistically significant anti-microbial effects compared with CPC in dentifrices (p＜0.05). Especially, polymer-combined CPC showed most effective for inhibition of Streptococcus mutans.
Conclusion: The antimicrobial activity of CPC was enhanced by combining polymer in dentifrices.
키워드
antibacterial agents; cetylpyridinium; chlorhexidine; dentifrices; polymers
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